The thyroid gland is a small but extremely important gland for the human body. Unfortunately, its small size does not at all mean that it can cause few problems. Quite the contrary. Hormones secreted by the thyroid affect most cells. Therefore, all diseases that affect the thyroid cause many problems. One of the more common ones, namely Hashimoto's disease, is no different.
- weight gain
- dryness of the skin
- joint pains
- hair loss
- pallor of the skin
- constantly feeling cold
Unfortunately, modern medicine does not have a cure for Hashimoto's disease. The inflammation, which smoulders for years, and the damaging effect of antibodies lead to the destruction of the thyroid parenchyma and inhibition of its function. Therapy is based on taking a levothyroxine analogue - the most important hormone produced by the thyroid gland, which is, of course, a synthetic made in a laboratory. And every drug, as we know, carries with it the possibility of side effects. The most common, when using synthetic levothyroxine, are cardiac arrhythmias and osteoporosis.
Hashimoto's disease can have a variety of origins. When it is known, it is possible to modify its course by suppressing inflammation. But it is easier to do this in relation to conditions that accompany the disease, such as those with an allergic background, e.g. atopic dermatitis or allergic rhinitis (hay fever). If the allergens that exacerbate the symptoms (e.g. pollen or cow's milk protein) can be found, this opens up the possibility of reducing the inflammation leading to destruction of the thyroid gland by eliminating them.
Anti-inflammatory properties of CBD
Hashimoto's disease is an autoimmune inflammation of the thyroid gland, and scientific studies show that one of the predominant properties of cannabidiol is precisely the anti-inflammatory effect. Scientists have been studying the effects of CBD on the human body for years, and more and more scientific publications are proving the positive effects of cannabidiol on the various types of inflammation that happen in the body. Hemp is therefore beginning to be increasingly studied for its effects on patients affected by various inflammatory diseases such as bronchial asthma, rheumatoid arthritis and type I diabetes. Studies have also been conducted on the effects of cannabidiol on Hashimoto's disease.
CBD - Endocannabinoid system - Hashimoto's disease
Not only anti-inflammatory properties CBD oils are being studied in the context of Hashimoto's disease. Also, their effects on Endocannabinoid system (ECS), which is a collection of receptors and transmitter substances that are a specific communication system in the human body. The ECS helps to maintain homeostasis in the body by regulating various physiological functions. In contrast, cannabidiol affects ECS structures, particularly the CB2 receptor, which may explain its anti-inflammatory effects.
Yet another group of researchers noted that CB1 receptors in the Endocannabinoid System control hormone production in the thyroid gland. And since CBD acts as a modulator of the ECS there is a chance that it could be useful in regulating thyroid conditions as it interacts with its structures.
However, to confirm the long-term efficacy of CBD in the treatment of Hashimoto's, more human clinical trials are needed. Many discoveries regarding CBD oils are therefore still to come.
- "Evidence for a functional cannabinoid CB1 receptor expressed in the rat thyroid gland"; Anna Porcella, Giorgio Marchese, Maria Antonietta Casu, Antonio Rocchitty, Maria Letizia Lai, Gian Luigi Gessa, Luca Pani (2002) https://pubmed.ncbi.nlm.nih.gov/12153749/
- "Role of cytokines in pathogenesis and suppression of thyroid autoimmunity"; Balaji B. Ganesh, Palash Bhattacharya, Anupama Gopisetty , and Bellur S. Prabhakar (2011) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3189552/
- "Clinical significance of CB1 and CB2 cannabinoid receptor expression in human malignant and benign thyroid lesions"; Eleftheria Lakiotaki, Constantinos Giaginis, Maria Tolia, Paraskevi Alexandrou, Ioanna Delladetsima, Ioanna Giannopoulou, George Kyrgias, Efstratios Patsouris and Stamatios Theocharis. (2015) https://www.hindawi.com/journals/bmri/2015/839403/